ORGANIC CHEMISTRY Chapter 21 o Benzyne intermediates have been "trapped" though the use of Diels-Alder reactions COH C-0 ch3 (ch2)4ONO CHoC NH2 CO O Br KNH2 Department of Chemistry, Xiamen UniversityORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 21 Benzyne intermediates have been “trapped” though the use of Diels-Alder reactions. CO2H NH2 + CH3(CH2)4ONO H+ CH2Cl2 C N2+ O O CO2 N2 O O Br KNH2 * O O * *