Chromosome disorders After listening to this lecture you should have a better understanding of 1. The role karyotype analysis in the discovery and diagnosis of human chromosome disorders 2. The molecular and cellular origins of chromosome abnormalities 3. Several famous chromosome disorders 4. The role of dNa methylation in the regulation of gene expression and human diseaseChromosome disorders After listening to this lecture you should have a better understanding of: 1. The role “karyotype” analysis in the discovery and diagnosis of human chromosome disorders 2. The molecular and cellular origins of chromosome abnormalities 3. Several famous chromosome disorders 4. The role of DNA methylation in the regulation of gene expression and human disease