granular convoluted tubule, GCT. a segment convoluted duct between intercalated duct and striated duct in submandibular gland epithelial cell pyramidal in shaped, with large N apical cytoplasma: eosinophilic granules granules contain: growth factors-NGF, EGF, MGF, EGSF, EGF ii. homeostasis factors: renin, Kallikrein, CSF. ACF .digestive enzymes: amylase, ribonuclease, acid phosphatase iV. intracellular regulating factor* granular convoluted tubule, GCT: ---a segment convoluted duct between intercalated duct and striated duct in submandibular gland ---epithelial cell: pyramidal in shaped, with large N apical cytoplasma: eosinophilic granules granules contain: i. growth factors-NGF, EGF,MGF, EGSF, EGF ii. homeostasis factors: renin, Kallikrein, CSF, ACF iii. digestive enzymes: amylase, ribonuclease, acid phosphatase iv. intracellular regulating factor