CLASSICAL PATHWAY LECTIN PATHWAY ALTERNATIVE PATH Antigen antibody complex Mannan-binding lectin binds mannose on pathogen surface Pathogen surfaces 图 MBLMASP 3 & C3 convertase Temminal complement compone C4a* ●5b C3a,C5a C36 C7 8 c9 Peptide mediators Binds to complement Membrane-attack of inflammation, receptors on phagocytes complex, phagocyte recruitment lsis of certain pathogens and oell Opsonization of pathogens Removal of immune complexes