10.4 Mutations identify the operator and the regulator gene Inducer binding DNA binding Oligomerization 闷C canr oligomerize 闷C 闷C 50 100 150 200 250 300 350 Figure 10 10 Mutations map the regions of the lacl gene responsible for different functions. The DNA-binding domain is identified by lacl-d mutations at the N terminal region; lacl mutations unable to form tetramers are located between residues 220-280. Other lacl- mutations occur throughout the gene lacl mutations occur in 请莘大 regularly spaced clusters between residues 62-300Figure 10.10 Mutations map the regions of the lacl gene responsible for different functions. The DNA-binding domain is identified by lacI-d mutations at the N￾terminal region; lacl- mutations unable to form tetramers are located between residues 220-280. Other lacI- mutations occur throughout the gene. lacIs mutations occur in regularly spaced clusters between residues 62-300. 10.4 Mutations identify the operator and the regulator gene