Choline esters Acetylcholine(Ach,乙酰胆碱) PHarmacological actions Directly activate M, N-R .o muscarinic actions: in small dose nicotinic actions: in large dose Effective in large dose iv Local effect by im, sc[Pharmacological actions] Directly activate M, N-R ❖ muscarinic actions: in small dose ❖ nicotinic actions: in large dose Acetylcholine (Ach,乙酰胆碱) Effective in large dose iv Local effect by im, sc Choline esters