Serotonin system Serotonin system raphe nuclei cells fire most Basal ganglia rapidly during wakefulness, when an animal is aroused Neocortex Thalamus and active. is intimately involved in the control of sleep-wake cycles,as well as the different stages of sleep. Is a part of ascending reticular activating system (上行网状觉醒系统) Hypothalamus Is implicated in the control Temporal lobe of mood and certain types of emotional behavior. Cerebellum Raphe nuclei To spinal cord 1717 Serotonin system • raphe nuclei cells fire most rapidly during wakefulness, when an animal is aroused and active. • is intimately involved in the control of sleep‐wake cycles, as well as the different stages of sleep. • Is a part of ascending reticular activating system （上行网状觉醒系统） • Is implicated in the control of mood and certain types of emotional behavior