Stages of Response to Infection Adherence to Local infection. Local infection epithelium penetration of epithelium of tissues Lymphatic spread Adaptive immunity Protection against infection Nommal fiora Wound healing Complement Phagocytes Spedific antibody Local chemical facors Antbacterial proteins (altemative pathway) Antigen trapping T-cell dependent Phagocyies and peptides Phagocytes,cytokines NK cells macrophage activation (especially in lung) Phagocyles NK cells,activation Cytotoxic T cells yǒToes? of macrophages 1997 Current Biology Ltd./Garland Publishing,Inc. Stages of Response to Infection