2. Singer and Nicolson's Model of membrane structure: The fluid-mosaic model is the " central dogma" of membrane biology. A. The core lipid bilayer exists in a fluid state, capable of dynamic movement B Membrane proteins form a mosaic of particles penetrating the lipid to varying degrees. (outside of cell membrane protein The fluid mosaic glycoprotein Model, proposed in cholesterol 1972 by Singer and phospholipid Nicolson had two key features, both 。 implied in its name (cytoplasm inside of cell2. Singer and Nicolson’s Model of membrane structure: The fluid-mosaic model is the “central dogma” of membrane biology. A. The core lipid bilayer exists in a fluid state, capable of dynamic movement. B. Membrane proteins form a mosaic of particles penetrating the lipid to varying degrees. The Fluid Mosaic Model, proposed in 1972 by Singer and Nicolson, had two key features, both implied in its name