Nw.cab.zju.edu.cn/cab/ xueyuanxiashubumen/nx/ bioinplant.htm《生物信息学札记》樊龙江 False positive(假阳性) a positive data point collected in a data set that was incorrectly reported due to a failure of the test. If the test had correctly measured the data point, the data would have been recorded as negative Feed- -forward neural network(反向传输神经网络) Organizes nodes into sequence layers in which the nodes in each layer are fully connected with the nodes in the next layer, except for the final output layer. Input is fed from the input layer through the layers in sequence in a feed-forward direction, resulting in output at the final layer. See also Neural network Filtering(window size) During pair-wise sequence alignment using the dot matrix method, random matches can be filtered out by using a sliding window to compare the two sequences. Rather than comparing a single sequence position at a time, a window of adjacent positions in the two sequences is compared and a dot indicating a match, is generated only if a certain minimal number of matches occur Filtering(过滤) Also known as Masking. The process of hiding regions of (nucleic acid or amino acid) sequence having characteristics that frequently lead to spurious high scores. See SEG and dUST. Finished sequence(完成序列 Complete sequence of a clone or genome, with an accuracy of at least 99.99% and no gaps Fourier analysis Studies the approximations and decomposition of functions using trigonometric polynomials Format(file)(格式) Different programs require that information be specified to them in a formal manner, using particular keywords and ordering. This specification is a file format Forward-backward algorithm sed to train a hidden Markov model by aligning the model with training sequences. The algorithm then refines the model to reduce the error when fitted to the given data using a gradient descent approach FTP( Fille Transfer protoco)(文件传输协议) Allows a person to transfer files from one computer to another across a network using an FTP-capable client program. The FTP client program can only communicate with machines that run an FTP server. The server, in turn will make a specific portion of its tile system available for FTP access providing that the client is able to supply a recognized user name and password to the server Full shotgun clone(鸟枪法克隆) A large- insert clone for which full shotgun sequence has been producedwww.cab.zju.edu.cn/cab/xueyuanxiashubumen/nx/bioinplant.htm 《生物信息学札记》 樊龙江 False positive （假阳性） A positive data point collected in a data set that was incorrectly reported due to a failure of the test. If the test had correctly measured the data point, the data would have been recorded as negative. Feed-forward neural network （反向传输神经网络） Organizes nodes into sequence layers in which the nodes in each layer are fully connected with the nodes in the next layer, except for the final output layer. Input is fed from the input layer through the layers in sequence in a “feed-forward” direction, resulting in output at the final layer. See also Neural network. Filtering (window size) During pair-wise sequence alignment using the dot matrix method, random matches can be filtered out by using a sliding window to compare the two sequences. Rather than comparing a single sequence position at a time, a window of adjacent positions in the two sequences is compared and a dot, indicating a match, is generated only if a certain minimal number of matches occur. Filtering （过滤） Also known as Masking. The process of hiding regions of (nucleic acid or amino acid) sequence having characteristics that frequently lead to spurious high scores. See SEG and DUST. Finished sequence（完成序列） Complete sequence of a clone or genome, with an accuracy of at least 99.99% and no gaps. Fourier analysis Studies the approximations and decomposition of functions using trigonometric polynomials. Format (file)（格式） Different programs require that information be specified to them in a formal manner, using particular keywords and ordering. This specification is a file format. Forward-backward algorithm Used to train a hidden Markov model by aligning the model with training sequences. The algorithm then refines the model to reduce the error when fitted to the given data using a gradient descent approach. FTP (File Transfer Protocol)（文件传输协议） Allows a person to transfer files from one computer to another across a network using an FTP-capable client program. The FTP client program can only communicate with machines that run an FTP server. The server, in turn, will make a specific portion of its tile system available for FTP access, providing that the client is able to supply a recognized user name and password to the server. Full shotgun clone （鸟枪法克隆） A large-insert clone for which full shotgun sequence has been produced. 133