Tumor proliferation of Hsc Differentiation of hsc is blocked Leukemia cells are stopped on a differentiation stage of hsC lack of the normal function Proliferation is out of control and apoptosis is inhibited Leukemia cell is cloned and accumulated in a great quantity. infiltration and metastasis 2021/1/21 xie Yi, Hua Shan Hospital 52021/1/21 xie Yi,Hua Shan Hospital 5 Tumor proliferation of HSC Differentiation of HSC is blocked. Leukemia cells are stopped on a differentiation stage of HSC & lack of the normal function . Proliferation is out of control and apoptosis is inhibited. Leukemia cell is cloned and accumulated in a great quantity. infiltration and metastasis