Activation of transcription elongation by hiv tat protein I, Tat encoded by HIv is required for productive gene expression; 2, Tat binds to an rNA stem-loop structure called TAR, located at the 5-untranslated region of all HIV RNAS, 3 The protein-RNA complex may loop backwards and interact with the new initiation complex, resulting activation of the kinase activity of tFIh三、Activation of transcription elongation by HIV Tat protein 1、 Tat encoded by HIV is required for productive HIV gene expression; 2、Tat binds to an RNA stem-loop structure called TAR , located at the 5’-untranslated region of all HIV RNAs; 3、 The protein-RNA complex may loop backwoards and interact with the new initiation complex, resulting activation of the kinase activity of TFIIH