RF is a systemic disorder affecting Heart: pericarditis, myocarditis, and endocarditis, joint: polyarthritis skin: subcutaneous nodules and erythema ④ arteries: arteritis◼ RF is a systemic disorder affecting: ◼ ①heart: pericarditis, myocarditis, and endocarditis; ◼ ②joint: polyarthritis; ◼ ③skin: subcutaneous nodules and erythema; ◼ ④arteries: arteritis