BEH.462/3. 962J Molecular Principles of Biomaterials Spring 2003 Surface properties dominated by last layer deposited 图 s Polyanion 3)Polycation 2)Was Layer igure 2, Advancing contact angle as a function of the layer number --- termost layer, whereas even number films have chitosan as the outermost layer, Assemblyfiguresourcehttp://www.chem.fsuedu/multilayers/ mbly on complex surfaces o Polyelectrolytes will adsorb to surfaces with complex topography o Polyelectrolytes themselves may have complex geometries(e.g. particles or dendrimers )6 Scheme 1. Schematic llustration for the Preparation of Hollow 时9N2N9 PSS/4G PAMAM Multilayer Capsules 3. 4G PAMAM Colloid PSS/4G PAMAM- Generation 7 poly(amidoamine) dendrimer: template colloid coated colloid steps 1-4 Cure renoval PSS/4GPAMAM SS/4GPAMAM multilayer-coated colloid hollow capsule ( Khopade and Caruso, 2002) Dendrimerimagesourcehttp://www.foresight Lecture 9-polyelectrolyte hydrogels 60f17BEH.462/3.962J Molecular Principles of Biomaterials Spring 2003 Surface properties dominated by last layer deposited: θ ƒ Assembly figure source: http://www.chem.fsu.edu/multilayers/ • Assembly on complex surfaces o Polyelectrolytes will adsorb to surfaces with complex topography o Polyelectrolytes themselves may have complex geometries (e.g. particles or dendrimers) 6 Generation 7 poly(amidoamine) dendrimer: (Khopade and Caruso, 2002) ƒ Dendrimer image source: http://www.foresight.org/Conferences/MNT7/Papers/Cagin3/ Lecture 9 – polyelectrolyte hydrogels 6 of 17