Parameters affecting solubility: Molecular structure: The general rule is that"like dissolves like".A polar solvent, like water,is able to dissolve ionic solutes and other polar substances.High dipole moment,the ability to form hydrogen bonds,and the acidic or basic nature (electron donor-acceptor ability)are important characteristics to increase solubility in water. Water is a good solvent for a numerous substances: It has a high dielectric constant(that reduces the attractive forces between the atoms into a crystalline structure) It is an amphiprotic substance,acting as an acid or as a base It can solvate substances by means of dipole-dipole,ion- dipole and hyrogen bonding interactions