FAVOR THROMBOSIS INHIBIT THROMBOSIS Extrinsic coagulation Inactivates thrombin, lactors Xa, IXa factors Va and villa ActiveproteinC-,ProteinC Exposure of membrane-bound Inhibit platelet tissue factor aggregation Platelet adhesion. Antithrombin Ill Held together by VWF PGl2, NO and Fibrinogen adenosine d phosphatase H lke Thrombomodulin molecule• Fig 5 - 6