Channel-mediated Copyrighte The McGraw a Componies, Inc, Permission required tor reproduction cr os round for re 3 3 cartoon models of Copyright e The McGraw-Hill Companies, Inc. Permission required for reproduction or display on channel integral membrane proteins that function as ion channels: the regulated opening and closing of these channels is Cross section the basis of how neurons function queous pore of ion channel– Channel-mediated 3 cartoon models of integral membrane proteins that function as ion channels; the regulated opening and closing of these channels is the basis of how neurons function