安徽医科大学国际教育学院教案与讲稿 Teaching Plan for International Students,AHMU Title of the course:Clinical Pharmacogenetics Chapter:13 Teacher's name:Qiong Huang Grade:2013 Department:Clinical Medicine,School of International Education Time:14:30-16:50 Date(D/M/Y):3/16/2016 Lecture Notes: [MODULES] 2min MODULE 1:Introduction to clinical pharmacogenetics MODULE 2:The purpose of clinical pharmacogenetics MODULE 3:SNPs and its significances MODULE 4:CYP phenotypes and effect MODULE 5:Pharmacogenetic principles and discuss [INTRODUCTION TO CLINICAL PHARMACOGENETICSI 3min 1.PHARMACOGENETICS:the study of the role of inheritance in inter-individual variation in drug response. 2.PHARMACOGENOMICS:the use of DNA sequence information to measure and predict the reactions of individuals to drugs. 3.Paradox of Modern Drug Development [PURPOSE OF PHARMACOGENETICS AND PHARMACOGENOMICS] 5min 1.The purpose of pharmacogenetics and pharmacogenomics:Pharmacology+Genetics Genetic predisposition to drug effect Individualized pharmacotherapy:The right drug at right dose for the right people Revolutionize medicine 2.Factors Determining Interindividual variations in Drug Response. 3.Heritability of Drug Metabolism and Diseases. [SNPS AND ITS SIGNIFICANCES] 5min 1.Single nucleotide polymorphisms:is a DNA sequence variation occurring when a single nucleotide-A,T,C or G-in the genome (or other shared sequence)differs between members of a biological species or paired chromosomes in a human. A Key to Human Individuality+ A key to interindividual variations in drug metabolism and response 2.Genotypes of SNPs 3.Hierarchy of Pharmacogenetic Information from Single Nucleotide Polymorphisms 4.Variation in human genomics ICYP PHENOTYPES AND EFFECTI 20min 1.Drug-metabolizing enzyme genotype and plasma drug concentration 3安徽医科大学国际教育学院教案与讲稿 3 Teaching Plan for International Students, AHMU Title of the course: Clinical Pharmacogenetics Chapter: 13 Teacher’s name: Qiong Huang Grade: 2013 Department: Clinical Medicine, School of International Education Time: 14:30—16:50 Date (D/M/Y): 3/16/2016 Lecture Notes: [MODULES] 2min MODULE 1: Introduction to clinical pharmacogenetics MODULE 2: The purpose of clinical pharmacogenetics MODULE 3: SNPs and its significances MODULE 4: CYP phenotypes and effect MODULE 5: Pharmacogenetic principles and discuss [INTRODUCTION TO CLINICAL PHARMACOGENETICS] 3min 1. PHARMACOGENETICS: the study of the role of inheritance in inter-individual variation in drug response. 2. PHARMACOGENOMICS: the use of DNA sequence information to measure and predict the reactions of individuals to drugs. 3. Paradox of Modern Drug Development. [PURPOSE OF PHARMACOGENETICS AND PHARMACOGENOMICS] 5min 1. The purpose of pharmacogenetics and pharmacogenomics:Pharmacology + Genetics
Genetic predisposition to drug effect
Individualized pharmacotherapy: The right drug at right dose for the right people
Revolutionize medicine 2. Factors Determining Interindividual variations in Drug Response. 3. Heritability of Drug Metabolism and Diseases. [SNPS AND ITS SIGNIFICANCES] 5min 1. Single nucleotide polymorphisms: is a DNA sequence variation occurring when a single nucleotide — A, T, C or G — in the genome (or other shared sequence) differs between members of a biological species or paired chromosomes in a human.
A Key to Human Individuality+
A key to interindividual variations in drug metabolism and response 2. Genotypes of SNPs 3. Hierarchy of Pharmacogenetic Information from Single Nucleotide Polymorphisms 4. Variation in human genomics [CYP PHENOTYPES AND EFFECT] 20min 1. Drug-metabolizing enzyme genotype and plasma drug concentration