Diagnosis and accessory examinations Diagnosis can be based on history of unprotected sexual contact with high-risk sexual partner(s)or history of HsV infection of partner(s) typical clinical manifestations. Differential diagnosis include chancre chancroid Behcet's syndrome Both virologic(cell culture/PCR assay)and type- specific serologic tests are of value in confirmation of the infectionDiagnosis and accessory examinations Diagnosis can be based on – history of unprotected sexual contact with high-risk sexual partner(s) or history of HSV infection of partner(s) – typical clinical manifestations. Differential diagnosis include – chancre – chancroid – Behcet’s syndrome Both virologic (cell culture / PCR assay) and typespecific serologic tests are of value in confirmation of the infection