5.1.2 Basic Equation for Design of Bio-Reaction (1) Mass balance(Accumulatn is o under steady state Calculation of Mass balance for substrates and products converted Input Output Accumulation components components components+ /unit of components /unit volume /unit volume /unit volume volume Calculation of mass balance for cells Input Output Grown Died cels cells cells Accumulate ceus /unit /unit /unit d cellls /unit /unit volume volume volume volume volume5.1.2 Basic Equation for Design of Bio-Reaction （1）Mass balance（Accumulatn is 0 under steady state) Calculation of Mass balance for substrates and products Input components /unit volume = converted components /unit volume Output components /unit volume + + Accumulation of components /unit volume Grown cells /unit volume Accumulate d cells /unit volume Died cells /unit volume Output cells /unit volume Input cells /unit volume = + + + Calculation of Mass balance for cells