Neonatal bilirubin metabolism (Contd 2. Defective hepatic uptake of bilirubin from plasma a Decreased ligandin (Y and z protein b Binding of ligandin by other anionsNeonatal bilirubin metabolism (Contd.) 2. Defective hepatic uptake of bilirubin from plasma a. Decreased ligandin (Y and Z protein) b. Binding of ligandin by other anions