Part 1 Introduction 1. Empirical endocrinology ·BC2000 Castration 1543 Vesalius.,“ pituata”→“ pituitary” 1835 Graves disease ·1855 Claud bernard,“ endocrine” Addison's disease 1889 Brown- Squard,“ Brown- Sequard elixir”• BC2000 Castration • 1543 Vesalius, “pituata” → “pituitary” • 1835 Graves disease • 1855 Claud Bernard, “endocrine” Addison's disease • 1889 Brown-Squard, “ Brown-Séquard Elixir” Part 1 Introduction 1. Empirical endocrinology