7.4.2 Protens synthesized can move or transport between compartments in different ways 1. There are four fundamentally different ways, by which proteins move through the membranes from one compartment into another and even insert into the membranes Gated transport, by which specific macromolecules, even macromolecule assemblies, move between two topological equivalent spaces in continuity through a pore complex, such as NPC (nuclear pore complex) or the channel complex outer membrane of Mit or ChI., although which also allows free diffusion of smaller molecules Transmembrane transport, the membrane-bound protein translocators by which specific proteins, unfolded usually, are directly translocated in snake-like way across the membrane from the cytosol into a space that is topologically distinct. Such as the transportors or translocators in ER membrane (for initial translocation of novel peptide), the membrane of mit or chl7.4.2 Protens synthesized can move or transport between compartments in different ways 1. There are four fundamentally different ways, by which proteins move through the membranes from one compartment into another and even insert into the membranes: Gated transport, by which specific macromolecules, even macromolecule assemblies, move between two topologically equivalent spaces in continuity through a pore complex, such as NPC (nuclear pore complex) or the channel complex outer membrane of Mit or Chl., although which also allows free diffusion of smaller molecules. Transmembrane transport, the membrane-bound protein translocators by which specific proteins, unfolded usually, are directly translocated in snake-like way across the membrane from the cytosol into a space that is topologically distinct. Such as the transportors or translocators in ER membrane (for initial translocation of novel peptide), the membrane of Mit or Chl