How is a karyotype(核型 pl repared? Sample: blood, skin, amnio, cvs Cells grown in culture Blocked in metaphase using colchicine Spread on slide and stained Abnormalities detected by number, morphology and banding patternHow is a karyotype（核型） prepared? • Sample: blood, skin, amnio, CVS • Cells grown in culture • Blocked in metaphase using colchicine • Spread on slide and stained • Abnormalities detected by number, morphology and banding pattern