r Using computational or computational or bioinformatics approaches, to undertake large-scale genomic comparisons of both the casing and noncoding regions of various organIsms. r The methods of molecular biology depend upon and were developed from, an understanding of the properties of biological macromolecules themselvesUsing computational or computational or bioinformatics approaches,to undertake large-scale genomic comparisons of both the cosing and noncoding regions of various organisms. The methods of molecular biology depend upon,and were developed from,an understanding of the properties of biological macromolecules themselves