Cell Mediated Responses IFN- Macrophage activation Th1 LZ- CTL activation LT. DTH responses IL-12 B cell activation-opsonising Ab MHC. peptlde APc Dfn L10 IL-4 IL-4 Humoral Responses Th2IL-10Bcellactivation-neutralising Ab IL-5 Eosinopl hil activation lL1-13 Fig. 2. Schemati f T helper cell diferentiation This dagram is a simpk summary of the cytokines that nthuenoe different aton of naive, ton-commatted cDr T eells into a T heper I or T helper 2 type, the cytokine pmfile asxatd with each T helper type, and the type of immuine responses these cytoknes promote Ab antibdy. APC- antigen presenting cll CTL cytotoxic T lymphocyte. DTI delayed type hypenensitivty, MHC -majur histoumpat bility omplex molecu Th T helper oell 12/13/201612/13/2016 复旦大学 免疫学课件 朱乃硕教授 13