NMR experimental observables providing structural information Backbone conformation from chemical shifts (Chemical Shift Index-CSI):W, Distance restraints from NOEs Hydrogen bond restraints Backbone and side chain dihedral angle restraints from scalar couplings Orientation restraints from residual dipolar couplings 1010 NMR experimental observables providing structural information • Backbone conformation from chemical shifts (Chemical Shift Index - CSI): ,  • Distance restraints from NOEs • Hydrogen bond restraints • Backbone and side chain dihedral angle restraints from scalar couplings • Orientation restraints from residual dipolar couplings