Example:Single mutation makes big difference 一个突变形造成巨大影响 Hemoglobin gene Sickle Cell hemoglobin Normal hemoglobin forms long,inflexible chains lormal Red Sickled Red Blood Cells Blood Cells Chromosome 11 镰刀形贫血 Sickle cell anemia Normal red blood cells are compact and flexible,enabling them to squeeze through small capillaries Sickled red blood cells are stiff and angular. causing them to become stuck in small capillaries2016/11/15 1 8 Example： Single mutation makes big difference 镰刀形贫血 Sickle cell anemia 一个突变形造成巨大影响