Four Major Activators of the Adrenergic System Hypoxia-response is mainly cardiovascular: increase in heart rate contractility(B1); vasodilation of blood vessels in muscle(β2) Hypoglycemia -response is mainly metabolic ( glycogenolysis 阝2anda1, gluconeogenesisβ2andc12, lipolysisβesp.β3, a2), but B2 vasodilation in muscle increases glucose delivery Hypothermia- piloerection( M), peripheral vasocontraction (Ol), thermogenesis(B) Hypotension-baroreceptor reflex 10• Hypoxia - response is mainly cardiovascular: increase in heart rate & contractility (b1 ); vasodilation of blood vessels in muscle (b2 ). • Hypoglycemia - response is mainly metabolic (glycogenolysis b2 and 1 , gluconeogenesis b2 and 1,2, lypolysis b esp. b3 , 2 ), but b2 vasodilation in muscle increases glucose delivery. • Hypothermia - piloerection (M), peripheral vasocontraction (1 ), thermogenesis (b) • Hypotension – baroreceptor reflex Four Major Activators of the Adrenergic System 10