The pyrimidine biosynthetic pathway P \ICase CHe HCO Glutamine +2 ATP+ HAN HN N-C-H Glutaral +2 ADP oNLF sCHr HIN C-H H Dihydroorotase>OH Steps>(co OMP decarboxylase Orotate phospho H H ribosyltransferase DHO dehydrogenase 一CH:O PPa-PRPE Coena Coenzyme C=0 QH H O- OH OH Dihydroorotate(DHO) Orotidine 5.Monophosphate (OMP)The pyrimidine biosynthetic pathway