Introduction 1955. Sewel tied up coronary of dog, loose suddenly ventricular fibrillation Kane tied up left entricular branch of coronary of rat ECG no obvious change relieve deligation arrhythmicIntroduction 1955, Sewel tied up coronary of dog， loose suddenly ventricular fibrillation。 Kane tied up left entricular branch of coronary of rat ECG no obvious change relieve deligation arrhythmic