1)侵袭力( evasiveness 病原菌突破宿主防线,并能于宿主体内定居、繁殖、扩散的能力。 Number of 进入 Invading Microbes 宿主细胞损伤/病变效应 入侵宿主防御系统 Portals of Entry Damage to Host Cells/ Penetration or Evasion Mucous membranes Cytopathic Effects of Host Defenses Respiratory tract Direct damage Gastrointestinal tract Capsules Toxins Genitourinary tract Cell wall components Exotoxins Conjunctiva Enzymes Endotoxins Skin Hypersensitivity Parenteral route Adherence Figure 15.8 Microbial mechanisms of pathogenicity. A summary of how microorganisms cause disease 2021/10/1818 2021/10/18 进入 宿主细胞损伤/病变效应 入侵宿主防御系统 1）侵袭力(invasiveness)： 病原菌突破宿主防线，并能于宿主体内定居、繁殖、扩散的能力