523 Griseofulvin(灰黄霉素 OCH3 OCH3 O O CH3O O CH Griseofulvin as marked in 1958, the primary site of action of it involves Binding to RNA. Manifestations include inhibition of hyphal cell-wall synthesis and cytoplasmic microtubules. Mainly used to treat the skin fungal infections. The side effects are gastrointestinal, allergic, and more frequently, moderate increase in fecal protoporphyrin5.2.3 Griseofulvin(灰黄霉素) OCH3 CH3O Cl O O O OCH3 CH3 Griseofulvin as marked in 1958, the primary site of action of it involves Binding to RNA. Manifestations include inhibition of hyphal cell-wall synthesis and cytoplasmic microtubules. Mainly used to treat the skin fungal infections. The side effects are: gastrointestinal, allergic,and more frequently, moderate increase in fecal protoporphyrin