7.2.3 How existing substitute affect the compound reactivity,the directing effect of electron-donating and electron-withdrawing groups,the acidity/basicity effect of the first substitute. 7.3.教学内容 7.3.1.the nomenclature of benzene and heterocycle compounds 7.3.2 reactions on the benzene ring and side chain,especially the a position 7.3.3 the Friedel-Crafts reaction,the Sandmeyer reaction 7.3.4 the oxidation reaction on the a-position 7.3.5 How the acidity/basicity of phenol,carboxylic acid,aniline is affected by the substitutes 7.3.6.synthesis practice,synthetic route design,protective groups 7.3.7 nomenclature and reaction for aromatic heterocycles,like pyridine,pyrole,thiophene,furan and other fused aromatic rings 7.4.教学方法 A combination of in class PPT,recommended reading assignment and discussion 5.教学评价 How well the students are involved in the class,feedback from student comments,quality of the teaching PPTs Section 8.Amino acid and nucleic acids 8.1.教学目标 8.1.1 master the 21 commonly essential amino acids,Zwitterionic property of amino acids,peptide and protein 8.1.2 the neucleic acid base,neucleoside,neucleotide,related DNA,RNA 8.2.教学重难点 8.2.1 construction of amide bond method7.2.3 How existing substitute affect the compound reactivity, the directing effect of electron-donating and electron-withdrawing groups, the acidity/basicity effect of the first substitute. 7.3.教学内容 7.3.1. the nomenclature of benzene and heterocycle compounds 7.3.2 reactions on the benzene ring and side chain, especially the α position 7.3.3 the Friedel-Crafts reaction, the Sandmeyer reaction 7.3.4 the oxidation reaction on the a-position 7.3.5 How the acidity/basicity of phenol, carboxylic acid, aniline is affected by the substitutes 7.3.6. synthesis practice, synthetic route design, protective groups 7.3.7 nomenclature and reaction for aromatic heterocycles, like pyridine, pyrole, thiophene, furan and other fused aromatic rings 7.4.教学方法 A combination of in class PPT, recommended reading assignment and discussion. 5.教学评价 How well the students are involved in the class, feedback from student comments, quality of the teaching PPTs. Section 8. Amino acid and nucleic acids 8.1.教学目标 8.1.1 master the 21 commonly essential amino acids, Zwitterionic property of amino acids, peptide and protein 8.1.2 the neucleic acid base, neucleoside, neucleotide, related DNA, RNA 8.2.教学重难点 8.2.1 construction of amide bond method