3/13/2016 Characteristics of Disease Characteristics of Disease Staphylococcal food poisoning is a self- limiting illness Symptoms develop within 6 hours after Vomiting occurs after an unusually short eafing time of onset,as little as 30 min Other common symptoms Average incubation time is 4.4 hours nausea Illness can appear within 30 min -cramps Death is rare,ranges from 0.03-4.4% diarrhea headaches ·1o%seek medical help Lack of fever is consistent with the illness ·Treatment is minimal being caused by a toxin and not an infection Toxic Dose Mechanism of Staphylococcal Enterotoxins-vomit Analyzed using recovered food from outbreaks Very toxic,1 ng of enterotoxin per gr of 2.Stimulation of food will cause illness vagus nerve Enterotoxin levels ingested range from 3.Transmits 0 signal to the 1-5g vomitting .aureus levels >105 cells/g may produce center in the brain the level of toxin required to cause illness intestinal epithelium 93/13/2016 9 Characteristics of Disease • Staphylococcal food poisoning is a self￾limiting illness • V iti ft ll h t Vomiting occurs after an unusually short time of onset, as little as 30 min • Other common symptoms - nausea - cramps - diarrhea - headaches • Lack of fever is consistent with the illness being caused by a toxin and not an infection Characteristics of Disease • Symptoms develop within 6 hours after eating • Average incubation time is 4.4 hours • Illness can appear within 30 min • Death is rare, ranges from 0.03-4.4% • 10% seek medical help • Treatment is minimal Toxic Dose • Analyzed using recovered food from outbreaks • Very toxic, 1 ng of enterotoxin per gr of food will cause illness • Enterotoxin levels ingested range from 1-5 g • S. aureus levels >105 cells/g may produce the level of toxin required to cause illness