Alkylation of ammonia or amines NaoH E Nh2 +rX 一RNH3X RNH 2 + Naoh RNH2+RX—-R2NH2x RONH ●● Naoh R2NH+R-X RBNH X R3N ①D ●● R3N+RⅩ RAN X ⑨D RI>RBr>RCl1°RX>2°RXOrganic Chemistry Organic Chemistry Xiamen Xiamen University University Alkylation of ammonia or amines NH 3 + R X RNH 3 X NaOH RNH 2 RNH 2 + R X R 2NH 2 X NaOH R 2NH R 2NH + R X R 3NH X NaOH R 3 N R 3 N + R X R 4N X RI > RBr > RCl 1 R X > 2 R X