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C Shared environments among relatives is a confounding factor in analyses aimed at quantifying genetic contributions to this disorder D. The relative liability of developing schizophrenia can be modeled as a quantitative trait that is normally distributed in the population and among sets of family members who share the same degree of relatedness to a proband with schizophrenia E. The chance of a person developing schizophrenia depends only upon types of genes the person has inherited from his/her parents 16. Which of the following is not considered to be complex disorder? A. Cancer B. Huntingtons disease C. Alzheimer's disease D. Parkinson's disease EType-2 diabetes 17. Which of the following is a false statement? A. The mitochondrial genome comprises circular double-stranded DNA containing 16.6 k bp B. The mitochondrial genome includes 37 genes: 13 protein coding genes, 22 tRNA genes and 2 ribosomal RNA genes C. Mitochondrial genes do not contain introns D. Mitochondria use the universal genetic code for the translation of proteins E. Mitochondrial tRNAs contain special modifications to allow the recognition of wobble nucleotides within degenerate codons 18. Which of the following is a false statement? A Mitochondrial DNA is replicated by DNA polymerase-gamma B DNA polymerase-gamma is encoded in the nuclear genome C. Mutations in DNA polymerase-gamma are the cause of several mitochondrial disorders, including, chronic progressive external ophthalmoplegia(CPEO) D. CPEO symptoms include the inability to move the eyes and the inability to fully open the eyelids E CPEO is always inherited from the mother 19. Which of the following is not a component of human nuclear chromosomes? A. D-loops B telomeres C. centromeres D. heterochromatin E euchromatin 20. Which of the following is a false statement? A. Prader-Willi syndrome is often caused by the loss of the abil ity to express genes from the paternally inherited chromosome that cannot be expressed from the maternally inherited chromosome due to imprintingC. Shared environments among relatives is a confounding factor in analyses aimed at quantifying genetic contributions to this disorder. D. The relative liability of developing schizophrenia can be modeled as a quantitative trait that is normally distributed in the population and among sets of family members who share the same degree of relatedness to a proband with schizophrenia. E. The chance of a person developing schizophrenia depends only upon types of genes the person has inherited from his/her parents. 16. Which of the following is not considered to be complex disorder? A. Cancer B. Huntington’s disease C. Alzheimer’s disease D.Parkinson’s disease E.Type-2 diabetes 17. Which of the following is a false statement? A. The mitochondrial genome comprises circular double-stranded DNA containing ~ 16.6 k bp. B. The mitochondrial genome includes 37 genes: 13 protein coding genes, 22 tRNA genes and 2 ribosomal RNA genes. C. Mitochondrial genes do not contain introns. D. Mitochondria use the universal genetic code for the translation of proteins. E. Mitochondrial tRNAs contain special modifications to allow the recognition of “wobble” nucleotides within degenerate codons. 18. Which of the following is a false statement? A. Mitochondrial DNA is replicated by DNA polymerase-gamma. B. DNA polymerase-gamma is encoded in the nuclear genome. C. Mutations in DNA polymerase-gamma are the cause of several mitochondrial disorders, including, chronic progressive external ophthalmoplegia (CPEO). D. CPEO symptoms include the inability to move the eyes and the inability to fully open the eyelids. E. CPEO is always inherited from the mother. 19. Which of the following is not a component of human nuclear chromosomes? A. D-loops B. telomeres C. centromeres D. heterochromatin E. euchromatin 20. Which of the following is a false statement? A. Prader-Willi syndrome is often caused by the loss of the ability to express genes from the paternally inherited chromosome that cannot be expressed from the maternally inherited chromosome due to imprinting
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