Nobel Prize in Physiology or medicine 1980 Discovery of MHC genes (histocompatibility genes),H-2gene Human transplantation antigens (HLA) Barui Benacerraf Jean Dausset George D Snell Nobel Prize in Physiology or medicine 1990 the treatment of human disease In 1954,the first successful human Joseph E.Murray E.Donnall Thomas➢ Discovery of MHC ➢ H-genes (histocompatibility genes), H-2 gene ➢ Human transplantation antigens (HLA) Baruj Benacerraf Jean Dausset George D. Snell Nobel Prize in Physiology or medicine 1980 Discoveries concerning organ transplantation in the treatment of human disease ➢ In 1954, the first successful human kidney transplant was performed between twins in Boston. Joseph E. Murray E. Donnall Thomas Nobel Prize in Physiology or medicine 1990