Difference between prokaryotic and eukaryotic regulation Transcription often is controlled at the stage of initiation. It may also be controlled at termination to prevent transcription from proceeding past a terminator to the gene(s) beyond. This is the primary control strategy for bacterial gene expression In eukaryotic cells, processing of the rna product may be regulated at the stages of modification, splicing, transport, or stability. In bacteria, an mRNa is in principle available for translation as soon as it is synthesized, and these stages of control are not avallableDifference between prokaryotic and eukaryotic regulation • Transcription often is controlled at the stage of initiation. It may also be controlled at termination to prevent transcription from proceeding past a terminator to the gene(s) beyond. This is the primary control strategy for bacterial gene expression • In eukaryotic cells, processing of the RNA product may be regulated at the stages of modification, splicing, transport, or stability. In bacteria, an mRNA is in principle available for translation as soon as it is synthesized, and these stages of control are not available