COOH ADP +P COOH H2N-C-H HN- C-H CH2 + H H20 = ATP C=O OH NH2 Glutamate ammonia-glutamine water COOH COOH NADP+ COOH COOH H,N-C-H C=0 HN-C-H HN-C-H CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 C=0 COOH C=O COOH NH2 NADPH H+ OH Glutamine a-keto-glutarate-glutamateglutamateGlutamate + ammonia → glutamine + water Glutamine + -keto-glutarate → glutamate + glutamate