1559T_ch21_373-38810/18/0518:42Pa9e373 EQA 21 Amines and Their Derivatives:Functional Groups Containing Nitrogen s that you will encounter in nic chemistry.The are not entirely new to you.of course.They p ane Mo ou have bee roduced to amin ine the erties of amines as a class of com pounds.It then fo cuses in more detail on the limitations and variatior on t mines are not involved in of disti nctly dif- ferent types of reactions.Thus.you should find this aspect of amine chemistry relatively manageable. Outline of the Chapter 21-1 Nomenclature 21z,213,2148cls2oeonndAcad8ae oup. 215,216,.2178ewdwg9mhicne 21-8 through 21-10 Reactions Mostly extensions of earlier material;a couple of special reactions.too. Keys to the Chapter 21-1.Nomenclature line-based name.The s nize that it works in much the same way that the IUPAC alcohol (alkanol)naming system works. 22hogh214epeaofAne 21-2 throu the same ess electronega- 373 21 Amines and Their Derivatives: Functional Groups Containing Nitrogen Amines represent the last of the simple functional groups that you will encounter in organic chemistry. They are not entirely new to you, of course. They popped up as early as Chapter 6, as the results of nucleophilic substitution reactions between ammonia and haloalkanes. More recently, you have been introduced to amine syntheses starting from carboxamides and nitriles (Sections 20-6 through 20-8). As usual, the chapter begins by presenting the usual body of descriptive information concerning the properties of amines as a class of com￾pounds. It then focuses in more detail on the limitations and variations associated with several amine synthe￾ses, finishing with sections on their reactions. Amines are of substantial importance biologically. But unlike other biologically important compound classes, amines are not involved in a very wide range of distinctly dif￾ferent types of reactions. Thus, you should find this aspect of amine chemistry relatively manageable. Outline of the Chapter 21-1 Nomenclature 21-2, 21-3, 21-4 Physical, Spectroscopic, and Acid-Base Properties of Amines Qualitative and quantitative characteristics of the functional group. 21-5, 21-6, 21-7 Synthesis Guidelines for choosing synthetic strategies. 21-8 through 21-10 Reactions Mostly extensions of earlier material; a couple of special reactions, too. Keys to the Chapter 21-1. Nomenclature To an even greater extent than with most other compounds, common names for amines are still almost uni￾versally used. It is therefore necessary to be able to recognize structures from either their alkylamine- or ani￾line-based name. The systematic alkanamine method looks tricky at first but becomes simple once you recog￾nize that it works in much the same way that the IUPAC alcohol (alkanol) naming system works. 21-2 through 21-4. Properties of Amines Amines are related to alcohols in the same way that ammonia is related to water. This parallel makes the prop￾erties of amines easy to predict, because the main qualitative difference is simply that N is less electronega- 373 1559T_ch21_373-388 10/18/05 18:42 Page 373