118 The UMAP Journal 28.2(2007) supply and Demand of Organs vs Year 品品2o苏s 941995199619971998 99200020012002200320042005 Figure 1. Number of transplants and cadaveric organ donors. Source: OPTN Annual Report 2005 [U.S. Organ Procurement .. 2005] type a have antigen a in their body, people with blood type B have antigen B, people with blood type AB have both, and people with blood type Ohave neither. a person with blood type AB can receive an organ from anyone, a person with blood type A or B can rece ive an organ from a person of blood type o or the same blood type, and a person with blood type O can receive an organ only from someone with typo blood Human Leukocyte Antigens(HLA): HLA indicates a persons tissue type, whose most important components are the A, B, and DR antigens, Each antigen consists of two alleles, and matching all six components results in a significantly increased success rate for kidney transplants. Patients with mismatched components, however, can still survive for many years [U.S Organ Procurement.. 2005]. o Panel Reactive Antibody(PRA): PRA is a blood test, measuring the per entage of the U.S. population that blood samples are likely to react with. It tests for the presence of antibodies, proteins that bind to foreign molecules [University of Maryland. 2004a]. Blood can become more sensitive due to previous transplants, blood transfusions, or pregnancies [Duquesnoy 2005]118 The UMAP Journal 28.2 (2007) a C7 0 C 0 0 56 Co IL .4 z 3 2 x 10' Supply and Demand of Organs vs. Year 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 Year 2005 Figure 1. Number of transplants and cadaveric organ donors. Source: OPTN Annual Report 2005 [U.S. Organ Procurement... 2005]. type A have antigen A in their body, people with blood type B have antigen B, people with blood type AB have both, and people with blood type 0 have neither. A person with blood type AB can receive an organ from anyone, a person with blood type A or B can receive an organ from a person of blood type 0 or the same blood type, and a person with blood type 0 can receive an organ only from someone with type 0 blood. o Human Leukocyte Antigens (HLA): HLA indicates a person's tissue type, whose most important components are the A, B, and DR antigens. Each antigen consists of two alleles, and matching all six components results in a significantly increased success rate for kidney transplants. Patients with mismatched components, however, can still survive for many years [U.S. Organ Procurement ... 2005]. * Panel Reactive Antibody (PRA): PRA is a blood test, measuring the per￾centage of the U.S. population that blood samples are likely to react with. It tests for the presence of antibodies, proteins that bind to foreign molecules [University of Maryland ... 2004a]. Blood can become more sensitive due to previous transplants, blood transfusions, or pregnancies [Duquesnoy 2005]. I I I I I I I I I ci p ci ci l F-if----Wait-lislt- 1---13--. Donors