目 Mechanism of Action曹 Mechanisms of damage Lysis of host cells Stop or interfere with cell growth Exaggerate normal physiological mechanisms By depressing or augmenting particular functions, toxins can kill without damaging any cells Tetanus toxin paralyzes body without affecting target neurons Cholera toxin speeds up normal excretory process, resulting in massive loss of water BIOL 533 Lecture 9BIOL 533 14 Lecture 9 Mechanism of Action • Mechanisms of damage – Lysis of host cells – Stop or interfere with cell growth – Exaggerate normal physiological mechanisms • By depressing or augmenting particular functions, toxins can kill without damaging any cells – Tetanus toxin paralyzes body without affecting target neurons – Cholera toxin speeds up normal excretory process, resulting in massive loss of water