Substance metabolic disorder and Clinical situation of Diabetic glucose utilization disorder-glucose decomposition decrease energy insufficient-starvation condition → polyphagia(多食) hyperglycemia -glucosuria hypertonicity diuresis→ polyuria(多尿) protein degradation dehydration thirst→ polydipsia(多饮) accentuation athrepsy(消瘦) lipolysis excessive hyperosmolar non ketotic diabetic coma ketonuria lipolysis excessive -ketoplasia excessive→ Ketonemia→ acidosis comaSubstance Metabolic Disorder and Clinical Situation of Diabetic ◼ glucose utilization disorder→glucose decomposition decrease→energy insufficient→starvation condition →polyphagia(多食） hyperglycemia →glucosuria →hypertonicity diuresis →polyuria（多尿） ◼ protein degradation↓dehydration thirst→polydipsia（多饮） accentuation┤ athrepsy （消瘦） lipolysis excessive hyperosmolar nonketotic diabetic coma ketonuria lipolysis excessive →ketoplasia excessive→Ketonemia→acidosis coma