3.9 Time-Division Multiplexing Definition Time-division multiplexing (Tdm) is the time interleaving of samples from several sources so that the information from these sources can be transmitted serially over a single communication channel1 3.9 Time-Division Multiplexing • Definition. Time-division multiplexing (TDM) is the time interleaving of samples from several sources so that the information from these sources can be transmitted serially over a single communication channel