Main concerns for human health e potential rIS chuan health involves 1)direct health effects(toxicity) 2)tendencies to provoke allergic reaction(allergenicity); 3)specific components thought to have nutritional or toXIc properties; 4)the stability of the inserted gene; s)nutritional effects associated with genetic modification 6)any unintended effects which could result fro the gene insertion. The three main issues debated are tendencies to provoke allergic reaction (allergenicity), gene transfer and outcrossing.Main concerns for human health The potential risks to human health involves: 1) direct health effects (toxicity), 2) tendencies to provoke allergic reaction (allergenicity); 3) specific components thought to have nutritional or toxic properties; 4) the stability of the inserted gene; 5) nutritional effects associated with genetic modification; 6) any unintended effects which could result from the gene insertion. The three main issues debated are tendencies to provoke allergic reaction (allergenicity), gene transfer and outcrossing