Cardiac muscle metabolism At rest, cardiac muscle consumes fatty acids to supply most of its energy (70% fatty acids vs. 30% carbohydrates Under fasting state, almost all of the energy comes from fatty acid oxidation Under anaerobicor ischemic conditions, glycolysis is required which consumes tremendous amounts of blood glucose and forms large amount of lactic acidsCardiac muscle metabolism • At rest, cardiac muscle consumes fatty acids to supply most of its energy (70% fatty acids vs. 30% carbohydrates). • Under fasting state, almost all of the energy comes from fatty acid oxidation. • Under anaerobic or ischemic conditions, glycolysis is required, which consumes tremendous amounts of blood glucose and forms large amount of lactic acids. 7