Alagille syndrome Description: autosomal dominant intrahepatic cholestasis syndrome absence of bile ducts associated with congenital heart disease Organs involved: liver(2 heart (1, 2) who is most affected onset of most symptoms s 1 year old(2) males and females equally Incidence/Prevalence: about 1 in 70,000 births of all races worldwide (2Alagille syndrome ◼ Description: autosomal dominant intrahepatic cholestasis syndrome ◼ absence of bile ducts ◼ associated with congenital heart disease ◼ Organs involved: ◼ liver (2) ◼ heart(1, 2) ◼ Who is most affected: ◼ onset of most symptoms ≤ 1 year old(2) ◼ males and females equally(1) ◼ Incidence/Prevalence: ◼ about 1 in 70,000 births of all races worldwide(2)