Microvascular function Effective tissue perfusion requires intact microvascular function Match blood flow to areas of highest metabolic activity Intrinsic control of blood flow: endothelial stretch receptors metabolic activity Extrinsic control of blood flow: autonomic nervous systemMicrovascular Function • Effective tissue perfusion requires intact microvascular function. • Match blood flow to areas of highest metabolic activity. • Intrinsic control of blood flow: endothelial stretch receptors, metabolic activity • Extrinsic control of blood flow: autonomic nervous system