国生 国生 Pre-metered multidose as single units Multidose bulk reservoir Diskhaler:GlaxoSmithKline Turbuhaler:AstraZeneca 1 2 3 iece cover 45 国上人烤 emete 国上生一 Nebulizers ④Nebulizer Liquid content is atomized by mechanical pressure. Produce a constant stream of aerosol particles. 国丝生一 圈生 Advantages of nebulizer Disadvantages of nebulizer Applicable to more varieties of drug Expensive and cumbersome equipment Need minimal coordination for inhalation Treatment times are somewhat lengthy Works with low inspiratory flows Medicine can be easily contaminated Breath-hold is not required for efficacy An external power source is needed 88 Shanghai Jiao Tong University Pre-metered multidose as single units • Diskhaler: GIaxoSmithKline Shanghai Jiao Tong University Multidose bulk reservoir • Turbuhaler: AstraZeneca Nebulizers Shanghai Jiao Tong University Nebulizer • Liquid content is atomized by mechanical pressure. • Produce a constant stream of aerosol particles. Shanghai Jiao Tong University Advantages of nebulizer • Applicable to more varieties of drug • Need minimal coordination for inhalation • Works with low inspiratory flows • Breath-hold is not required for efficacy Shanghai Jiao Tong University Disadvantages of nebulizer • Expensive and cumbersome equipment • Treatment times are somewhat lengthy • Medicine can be easily contaminated • An external power source is needed